Notice of Change to the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead

Effective November 22, 2013, the California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) changed the basis for the listing of 1,2-dibromo-3-chloropropane (DBCP), ethylene oxide and lead as known to the state to cause reproductive toxicity under the Safe Drinking Water and Toxic Enforcement Act of 1986¹.  The original listing date of February 27, 1987 for DBCP, ethylene oxide² and lead remains the same.

DBCP, ethylene oxide and lead were originally added to the Proposition 65 list as causing reproductive toxicity pursuant to Labor Code Section 6382(d) which is incorporated by reference in Health and Safety Code Section 25249.8(a).  Male and female reproductive toxicity and developmental toxicity are the general endpoints noted for lead and ethylene oxide, and male reproductive toxicity is noted for DBCP.  Based on changes to certain federal regulations that affect the bases for the original listings, OEHHA has accordingly changed the bases for listings for these chemicals to the “formally required to be labeled or identified” listing mechanism³.

DBCP, ethylene oxide and leadare required to be identified or labeled to communicate a risk of reproductive toxicity by federal Occupational Safety and Health Administration (OSHA) regulations.  In addition, the U.S. Environmental Protection Agency (U.S. EPA) also requires labels to communicate a risk of reproductive toxicity for ethylene oxide.

The bases for listing DBCP, ethylene oxide and leadwere described in a public notice published in the September 20, 2013, issue of the California Regulatory Notice Register (Register 2013, No. 38-Z.)  The title of the notice was “Notice of Intent to Change the Basis for Listing as Known to the State of California to Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead.” The publication of the notice initiated a public comment period that closed on October 21, 2013.  One public comment was received. 

Chemical Reference

• Ethylene Oxide
• Lead and Lead Compounds
• 1,2-Dibromo-3-chloropropane (DBCP)

Related Notices

• Notice of Intent to Change the Basis for Listing as Known to the State of California To Cause Reproductive Toxicity: 1,2-Dibromo-3-Chloropropane, Ethylene Oxide and Lead

  Sep 20, 2013