Notice of Addition of Documents and Information to Rulemaking File, Amendment to Section 12805: MADL for DEHP by Oral Exposure

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Pursuant to the requirements of Government Code sections 11346.8(d), 11346.9(a)(1), and 11347.1, the Office of Environmental Health Hazard Assessment (OEHHA) is providing notice that documents and other information which the agency has relied upon in proposing amendments to Title 22, California Code of Regulations, section 12805, have been added to the rulemaking file and are available for public inspection and comment.

The purpose of this notice is to enter all relevant documents into the Rulemaking File, OAL File No. Z-05-0614-06. All the documents included in this notice had not been previously included in the Rulemaking File, OAL File No. Z-05-0614-06, but have been considered by OEHHA in establishing the proposed maximum allowable dose levels (MADLs) for DEHP by oral exposure. Of these documents, one is the revised draft OEHHA document supporting the proposed MADLs for DEHP by oral exposure (OEHHA, 2006), two others (Koch et al., 2003 and Stedman’s Medical Dictionary, 27th edition, 2003) are cited in the revised draft MADL document (OEHHA, 2006) and listed in the References section of this document.

All other documents on the list below have been identified in the Bibliography section of the revised draft OEHHA document supporting proposed MADLs for DEHP by oral exposure (OEHHA, 2006). All the documents identified in the Bibliography section of the document have been considered by OEHHA staff but did not directly contribute to the development of the MADLs and were not cited in the main text in the OEHHA (2006) MADL document. Thus, these papers are sources of potentially relevant information. Some documents identified in this notice are research or review papers that became available to OEHHA after preparation of the draft MADL document was completed and released to the public for comment on June 24, 2005. OEHHA staff reviewed these papers as they became available, and determined that no substantial revision to the MADL document was necessitated by these papers.

These documents are available for inspection at the OEHHA’s office located at 1001 “I” Street, 19th Floor, Sacramento, CA from May 5, 2006 through May 22, 2006, between the hours of 8:00 a.m. and 5:00 p.m. If you have any comments regarding the documents and other information, OEHHA will accept written comments between (date) and (date). All written comments must be submitted to OEHHA by e-mail, mail, fax, courier or hand-delivered, no later than 5:00 p.m. on May 22, 2006 and addressed to:

Office of Environmental Health Hazard Assessment
Street Address: 1001 I Street, 19th Floor
Sacramento, CA 95814

Mailing Address: P.O. Box 4010
Sacramento, CA 95812

Fax No.: (916) 323-8803
Telephone: (916) 445-6900

Comments transmitted via email should be addressed to:

It is requested but not required that written statements or arguments be submitted in triplicate. All written comments received by May 22, 2006, which pertain to the above-listed documents and other information will be reviewed and responded to by OEHHA’s staff as part of the compilation of the rulemaking file.

Inquiries concerning the action described in this notice may be directed to OEHHA, in writing, at the address given above, or by telephone at (916) 445-6900.

Documents and information added to Notice File No. Z-05-0614-06:

Revised draft OEHHA document supporting proposed MADLs for DEHP by oral exposure:

Office of Environmental Health Hazard Assessment (OEHHA, 2006). Proposition 65 Maximum Allowable Dose Level (MADL) for Reproductive Toxicant for Di(2-ethylhexyl)phthalate (DEHP) by Oral Exposure. OEHHA Reproductive and Cancer Hazard Assessment Section, California Environmental Protection Agency, Sacramento, April.

Research papers or documents cited and listed as “References” in the OEHHA (2006) document:

Koch HM, Rossbach B, Drexler H, Angerer J (2003). Internal exposure of the general population to DEHP and other phthalates--determination of secondary and primary phthalate monoester metabolites in urine. Environ Res 93, 177-85.

Stedman's Medical Dictionary, 27th edition (2000). Pub. Lippincott Williams & Wilkins. Accessible online at

Research papers or documents listed in the Bibliography in the OEHHA (2006) document:

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