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Diaminotoluene (mixed) Delisted

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is removing a chemical from the list of chemicals known to the state to cause cancer, for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).

Diaminotoluene (mixed) was originally added to the Proposition 65 list under the authoritative bodies listing mechanism on January 1, 1990. Regulations governing the listing of chemicals under the authoritative bodies mechanism are published in Title 27, California Code of Regulations, Section 25306. OEHHA received a petition from Big Lots Stores, Inc. for reconsideration of listing for diaminotoluene (mixed) on October 21, 2014. While the US Environmental Protection Agency (US EPA) (1988) document that provided the basis for the listing indicates that the hazard ranking of diaminotoluene (mixed) “is applicable to all isomers of diaminotoluene”, and that the “evidence on potential carcinogenicity from animal studies is “sufficient”, the US EPA document also indicates that “this evidence is based on the carcinogenic properties of the isomer 2,4-diaminotoluene”. No other information on the mixture or individual isomers is included in the US EPA document. For this reason and in accordance with 27 CCR, Section 25306(j), OEHHA referred the chemical to the Carcinogen Identification Committee (CIC) for a recommendation concerning whether the chemical should continue to be included on the list of chemicals known to the state to cause cancer. At a public meeting on November 4, 2015, the CIC determined that diaminotoluene (mixed) has not been clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer. Therefore, diaminotoluene (mixed) is delisted effective November 20, 2015.

The reader is directed to the Notice to Interested Parties published in the August 28, 2015 issue of the California Regulatory Notice Register (Register 2015, No. 35-Z) for the supporting documentation which the CIC relied upon in making its determination. A complete, updated chemical list denoting these chemicals in strikeout is published elsewhere in this issue of the California Regulatory Notice Register.

The chemical delisted effective November 20, 2015 is shown below:

Carcinogens:

Chemical                                           CAS No.
Diaminotoluene (mixed)                      ---

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