Chemicals Listed Effective October 24, 1997 as Known to the State to Cause Cancer: 2,4,5-Trimethylaniline and its strong acid salts, 5-Chloro-o-toluidine and its strong acid salts, and Quinoline and its strong acid salts

The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency has added three chemicals to the list of chemicals known to the State to cause cancer, for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65). These chemicals are listed effective October 24, 1997.

2,4,5-Trimethylaniline and its strong acid salts, 5-chloro-o-toluidine and its strong acid salts, and quinoline and its strong acid salts are listed as carcinogens based upon a determination by the "state’s qualified experts" (the Carcinogen Identification Committee of OEHHA’s Science Advisory Board) that they have been clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer.

The reader is directed to the Notice to Interested Parties published in the June 13, 1997 issue of the California Regulatory Notice Register for the supporting documentation which the Committee relied upon in making its determination that the criteria for listing have been satisfied.

The three chemicals listed effective October 24, 1997, and the mechanism under which each is listed, are shown below:

Carcinogens

Chemical

CAS No.

Listing mechanism1

5-Chloro-o-toluidine and its strong acid salts

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SQE

Quinoline and its strong acid salts

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SQE

2,4,5-Trimethylaniline and its strong acid salts

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SQE

Footnotes and References

1Listing mechanism: SQE - "state’s qualified experts" mechanism

A complete, updated chemical list is published elsewhere in this issue of the California Regulatory Notice Register.