Chemicals Listed Effective April 2, 2010 as Known to the State to Cause Cancer: Bromochloroacetic Acid, Cumene and Diclofop-methyl

The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding Bromochloroacetic acid (CAS No. 5589-96-8), Cumene (CAS No. 98-82-8) and Diclofop-methyl (CAS No. 51338-27-3) to the list of chemicals known to the state to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65 ). The listing of bromochloroacetic acid, cumene and diclofop-methyl is effective April 6, 2010.

Bromochloroacetic acid (CAS No. 5589-96-8), cumene (CAS No. 98-82-8) and diclofop-methyl (CAS No. 51338-27-3) are being listed as chemicals known to the State of California to cause cancer. The listing of the chemicals bromochloroacetic acid and cumene is based on formal identification by an authoritative body (the National Toxicology Program (NTP)), that the chemicals cause cancer. The listing of diclofop-methyl is based on formal identification by the authoritative body, the U.S. Environmental Protection Agency (U.S. EPA), that the chemical causes cancer. The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 27, Cal. Code of Regs., section 25306.

The reader is directed to the Notices of Intent to List Bromochloroacetic acid (CAS No. 5589-96-8), Cumene (CAS No. 98-82-8) and Diclofop-methyl (CAS No. 51338-27-3) published in the February 5, 2010 issue of the California Regulatory Notice Register (Register 2010, No. 6 Z) for the documentation supporting OEHHA’s determination that the criteria for administrative listing have been satisfied for these chemicals.

OEHHA analyses of dose-response data to establish the no significant risk levels (NSRLs) for bromochloroacetic acid, cumene and diclofop-methyl under Proposition 65 have not yet been conducted. The priority status for the development of such analyses will be announced in a future OEHHA Proposition 65 Status Report for Safe Harbor Levels.

A complete, updated Proposition 65 list is published elsewhere in this issue of the California Regulatory Notice Register.

The table below summarizes the changes made today to the Proposition 65 list.

Bromochloroacetic acid (CAS No. 5589-96-8), Cumene (CAS No. 98-82-8) and Diclofop-methyl (CAS No. 51338-27-3) Listed as known to the state to cause Cancer

Chemical CAS Number Toxicological Endpoint Listing Mechanism
Bromochloroacetic acid 5589-96-8 Cancer AB
Cumene 98-82-8 Cancer AB
Diclofop-methyl 51338-27-3 Cancer AB