Chemicals Delisted Effective April 4, 2014 as known to the State of California to Cause Reproductive Toxicity: N-Butyl Glycidyl Ether, Diglycidyl Ether, Phenyl Glycidyl Ether, Methyl Isopropyl Ketone and α-Methyl Styrene
Effective April 4, 2014, Office of Environmental Health Hazard Assessment (OEHHA) is removing n-butyl glycidyl ether, diglyciyl ether, phenyl glycidyl ether, methyl isopropyl ketone and α-methyl styrene from the list of chemicals known to the State to cause reproductive toxicity for purposes of Proposition 65. n-Butyl glycidyl ether, diglycidyl ether, and phenyl glycidyl ether were added to the list on August 7, 2009; α-methyl styrene was added to the list on July 29, 2011; and methyl isopropyl ketone was added to the list on February 17, 2012.
These five chemicals were originally added to the Proposition 65 list as causing reproductive toxicity pursuant to Labor Code Section 6382(d), which is incorporated by reference in Health and Safety Code Section 25249.8(a). Based on changes to certain federal regulations that affect the bases for the original listings, OEHHA referred these chemicals to the Developmental and Reproductive Toxicant Identification Committee (DARTIC) for reconsideration. In its official capacity as the "state's qualified experts" at a public meeting held on March 19, 2014, the DARTIC determined that the five chemicals have not been clearly shown, through scientifically valid testing according to generally accepted principles, to cause reproductive toxicity and should be removed from the list. Regulations governing the listing of chemicals by the DARTIC are set out in Title 27, California Code of Regulations, section 25305(b)(1).
A complete, updated chemical list is published in this issue of the California Regulatory Notice Register and is available on the OEHHA website.
- Phenyl Glycidyl Ether
- α-Methyl styrene (alpha-Methylstyrene)
- Methyl isopropyl ketone
- Diglycidyl ether
- n-Butyl glycidyl ether
Chemical Reference
- March 19, 2014 Meeting of the Developmental And Reproductive Toxicant Identification Committee