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Chemical Listed Effective December 3, 2010 As Known To The State Of California To Cause Reproductive Toxicity: Avermectin B1 (abamectin)

If you would like to sort the list by CAS number or date, please download the list as an Excel document.  You can then sort the list by date, CAS number, or chemical name using MS Excel.  The Excel document also includes the listing mechanism for each chemical listing and the safe harbor level, if one has been adopted.  A hyperlink is provided for those chemicals for which the basis for listing documentation is available electronically.  A hyperlink is provided for those safe harbor levels for which the risk assessment documentation is available electronically.

The Office of Environmental Health Hazard Assessment (OEHHA) is adding one chemical to the list of chemicals known to the State to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65)1. The chemical is avermectin B1 (abamectin) (CAS No. 71751-41-2).  Avermectin B1 (abamectin) is listed effective December 3, 2010. 

Avermectin B1 (abamectin) (CAS No. 71751-41-2)is being listed as a chemical known to the State of California to cause developmental toxicity.  The listing of avermectin B1 (abamectin) is based on its formal identification by an authoritative body2 (the U.S. Environmental Protection Agency (U.S. EPA)), as a chemical causing developmental toxicity.  The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 27, Cal. Code of Regs., section 25306. 

The Notice of Intent to List Avermectin B1 (abamectin) (CAS No. 71751-41-2) was published in the June 27, 2008 issue of the California Regulatory Notice Register (Register 2008, No. 26‑Z).  That notice includes a discussion of the information relied on by OEHHA in making the determination that Avermectin B1 (abamectin) meets the criteria for administrative listing. 

OEHHA generally strives to propose a safe-harbor level pursuant to Title 27, Cal. Code of Regs., section 25801, within one year of the listing of a chemical if sufficient data are available for calculating a level.  Because of the importance of this chemical to California’s agriculture industry, there is a particular need to adopt a safe-harbor level to provide regulatory certainty.  OEHHA is committed to providing a safe-harbor level for avermectin B1 by no later than December 2011.  

A complete, updated chemical list is published in this issue of the California Regulatory Notice Register and is available on the OEHHA website at www.oehha.ca.gov.

In summary, the following chemical is being listed under Proposition 65 as known to the State to cause reproductive toxicity: 

Reproductive toxicity
Chemical CAS No. Toxicological Endpoints Listing Mechanism3
Avermectin B1(abamectin) 71751-41-2 developmental toxicity AB

 

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Footnotes and References

1Health and Safety Code section 25249.5 et seq.

2See Health and Safety Code section 25249.8(b) and Title 27, Cal. Code of Regs., Section 25306.

3Listing mechanism: AB – “authoritative bodies” mechanism (Title 27 Cal. Code of Regs., section 25306).