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Cancer Hazard Identification Documents for Bis(2-Chloro-1-Methylethyl) Ether, 1-Chloro-4-Nitrobenzene, Estragole, and Trichloroacetic Acid

Documents finalized on [12/30/99]

The California Environmental Protection Agency's Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).

The Carcinogen Identification Committee (CIC) of OEHHA's Science Advisory Board advises and assists OEHHA in compiling the list of chemicals known to the State to cause cancer which is mandated by Health and Safety Code Section 25249.8. The Committee serves as the State's qualified experts for rendering an opinion as to whether a chemical has been clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer.

On June 12, 1998 (California Regulatory Notice Register, Register 98, No. 24-Z), OEHHA requested information in relation to the preparation of draft hazard identification documents on six chemicals to be considered by the CIC. The 60-day data call-in ended on August 11, 1998. No information or data were received. Two of the six chemicals (2-aminofluorene and 4-amino-2-nitrophenol) were considered by the CIC at their December 10, 1998 meeting and were identified as clearly shown to cause cancer. 2-Aminofluorene and 4-amino-2-nitrophenol were added to the Proposition 65 list on January 29, 1999.

The draft hazard identification documents on the other four chemicals are currently available and are entitled: "Evidence on the Carcinogenicity of Bis(2-chloro-1-methylethyl) ether", "Evidence on the Carcinogenicity of 1-Chloro-4-nitrobenzene", "Evidence on the Carcinogenicity of Estragole", and "Evidence on the Carcinogenicity of Trichloroacetic acid". Copies of the draft documents are available from the Proposition 65 Implementation Office and may be requested by calling (916) 445-6900. The documents are also available through the Internet. This notice marks the beginning of a 60-day public comment period. Comments should be sent by mail or fax to:

the Proposition 65 Office
Office of Environmental Health Hazard Assessment
Post Office Box 4010
Sacramento, CA 95812-4010

FAX (916) 327-1097

In order to be considered, comments must be received at OEHHA by 5:00 p.m. on Tuesday, September 14, 1999.

OEHHA will organize and index the comments received and forward the information to the CIC members at least two weeks prior to the meeting at which the candidate chemical will be considered. The next meeting of the CIC is scheduled for October 7, 1999. The meeting will begin at 10:00 a.m. in Training Room A, Elihu Harris State Building, 1515 Clay Street, Oakland California, and will last until all business has been conducted or until 5:00 p.m.

Note: The final hazard identification documents report in the preface the final action taken by the Carcinogen Identification Committee at its meeting on October 7, 1999. Typographical corrections may have been made to the document, but the technical content of the documents is the same as that released as draft on July 16, 1999.

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