Bisphenol S (BPS) Added to the Proposition 65 List for Male Reproductive Toxicity

Bisphenol S: Male Reproductive Toxicant  

Effective January 3, 2025, the Office of Environmental Health Hazard Assessment (OEHHA) has added the male reproductive toxicity endpoint to the listing of bisphenol S (BPS) on the Proposition 65 list for reproductive toxicity. This listing was done via the “State’s Qualified Experts” mechanism, based on the Developmental and Reproductive Toxicant Identification Committee’s (DARTIC) determination that this chemical was clearly shown to cause male reproductive toxicity. BPS was first placed on the Proposition 65 list for reproductive toxicity, based on the female reproductive endpoint, on December 29, 2023. 

• BPS Listing Notice
• Complete, updated Proposition 65 chemical list

A summary and agenda of the 2024 DARTIC meeting can be found in the Downloads section below. 

Bisphenol S: Female Reproductive Toxicant

Effective December 29, 2023, the Office of Environmental Health Hazard Assessment (OEHHA) has added bisphenol S (BPS) to the Proposition 65 list as a reproductive toxicant (female reproductive endpoint). This listing was done via the “State’s Qualified Experts” mechanism, based on the Developmental and Reproductive Toxicant Identification Committee’s (DARTIC) determination that this chemical was clearly shown to cause female reproductive toxicity.

The warning requirement for significant exposures to BPS took effect on December 29, 2024.

• BPS Listing Notice

A summary and agenda of the 2023 DARTIC meeting can be found in the Downloads section below. 

Data Call-In

On March 4, 2022, OEHHA started a data call-in process to solicit information on BPS from the public. 

• Request for relevant information on the potential reproductive toxicity of BPS