Additional Information on Chlorpyrifos - Toxicity Profile

On September 5, 2008, the Office of Environmental Health Hazard Assessment (OEHHA) released a hazard identification document (HID) for chlorpyrifos as a candidate for listing as known to cause reproductive toxicity under Proposition 65.  The Developmental and Reproductive Toxicant Identification Committee (DARTIC) of OEHHA’s Science Advisory Board will determine whether chlorpyrifos has been clearly shown to cause reproductive toxicity at a public meeting to be held on November 20, 2008.

It was recently brought to the attention of OEHHA that a relevant study of the developmental toxicity of chlorpyrifos had been inadvertently omitted from the HID.  In order to allow the DARTIC to review as complete a data set as possible, OEHHA has provided the Committee with a summary of the study equivalent to the summaries provided for other studies in the HID, as well as a copy of the entire study report.  A copy of the study summary can be obtained at www.oehha.ca.gov , or by calling the Proposition 65 Implementation Office at (916) 445-6900.

Rubin, Y., A. Nyska, and T. Waner (1987). Pyrinex teratogenicity study in the rabbit Conducted at Life Science Research Israel Ltd., Laboratory Study # MAK/103/PYR.

Chemical Reference

• Chlorpyrifos

Meeting Announcements/Information

• November 20, 2008 Developmental and Reproductive Toxicant Identification Committee Meeting

Related Notices

• Hazard ID Materials for Hexavalent Chromium and Chlorpyrifos, Submission of Relevant Studies for Particulate Matter and Total Trihalomethanes

  Sep 5, 2008
• Request for Relevant Information on the Developmental and Reproductive Toxicity of: Bisphenol-A, Chlorpyrifos, Chromium, DDE, Sulfur dioxide

  Jan 18, 2008
• Additional Information on Chlorpyrifos

  Nov 3, 2008