Nickel Carbonyl

CAS Number

13463-39-3

Nickel Carbonyl

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1:	2.6 E-4
Inhalation Slope Factor (mg/kg-day)-1:	9.1 E-1
Oral Slope Factor (mg/kg-day)-1:	9.1 E-1
Comments/References:	OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011. Listed as Nickel and nickel compounds.

Air

Acute RELs

Acute REL (μg/m3):	0.2
Species:	Mouse
Acute REL Toxicologic Endpoint:	Depressed antibody response
Acute REL Target Organs:	Immune system
Last Acute REL Revision:	2012
Acute Reference Exposure Levels Comments:	Inhalation concentrations as micrograms Ni/m3. OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds.

8-Hour RELs

8-Hour Inhalation REL (μg/m3):	0.06
Last 8-Hour REL Revision:	2012
8-Hour Reference Exposure Levels Comments:	Inhalation concentrations as micrograms Ni/m3. OEHHA 2013. Technical Support Document for Noncancer RELs, Appendix D1. Updated July 2014. Listed as Nickel & nickel compounds.

Chronic REL

Chronic Inhalation REL (μg/m3):	0.014 (inhalation); 11 μg/kg BW-day (oral)
Chronic Target Organs:	Inhalation: Respiratory system, hematologic system. Oral: Development
Human Data:	No
Last Chronic REL Revision:	2012
Chronic Reference Exposure Levels Comments:	Inhalation concentrations as micrograms Ni/m3; oral dose as micrograms Ni/kg-day. OEHHA 2012. Nickel Reference Exposure Levels. Listed as Nickel & nickel compounds (except nickel oxide for chronic inhalation exposures).

Proposition 65

Chemical Status

Cancer:	Currently listed
Reproductive Toxicity :	Currently listed

Cancer

Cancer - Listing Mechanism

State's Qualified Experts

Listed as causing :	Listed as causing: Cancer
Date of Listing:	10/01/1987

Reproductive Toxicity

Listed as causing:	Developmental Toxicity
Developmental Toxicity
Date of Listing:	09/01/1996
Basis for Listing :	Authoritative Bodies-US Environmental Protection Agency

Comments

Listed as Nickel carbonyl.

Public notices related to this chemical

Clarification of Chemical Listing of Nickel and Certain Nickel Compounds and Request for Comment on Proposed Listing of Nickel Compounds as Known to Cause Cancer

Water

California Public Health Goals Data

Health Risk Category:	Developmental toxicity (increased neonatal deaths)
Cancer Risk at PHG:	n/a
MCL value (mg/L):	0.1
Cancer Risk at MCL:	n/a
Last PHG Revision :	2001
California PHG Comments:	Not considered an oral carcinogen; PHG based on reproductive toxicity. OEHHA 2001. Public Health Goal for Nickel. PHG applies to soluble nickel compounds.