Results of the Third Round Pilot Random Selection of the Chemicals Eligible for Prioritization for Consideration of Carcinogenicity Evaluation

The California Environmental Protection Agency's Office of Environmental Health Hazard Assessment (OEHHA) announces the results of the third round pilot random selection process of the chemicals eligible for prioritization. The selected chemicals will be considered for carcinogenicity evaluation.

In a public notice published in the California Regulatory Notice Register (CRNR) on October 26, 2001, OEHHA announced the availability of the alphabetical listing of candidate chemicals for the third round pilot random selection. In the October 26th notice, OEHHA identified 100 chemicals that could potentially be considered by the State's qualified experts (i.e., the Carcinogen Identification Committee of OEHHA's Science Advisory Board). The 100 chemicals were listed in "Table 1: Candidates for Random Selection Third Round" (see attached Table 1). Also, as explained in the October 26th notice, the seed number for the third round pilot random selection was determined by summing the first three numbers (27, 28, 10) drawn from the California Super Lotto Plus on Saturday, October 27, 2001 to yield 65. Beginning with the 65th number (59) and ending with the 164th number (278) on "Table 2 Random Numbers", each of the 100 chemicals had a unique random numerical value assigned to it. These 100 assigned random numbers, and corresponding chemicals, were reordered according to increasing value. The first 50 numerical values constitute the candidate chemicals in the third round random selection (see attached Table A: Third Round Randomly Selected Candidates for Carcinogenicity Evaluation). A list of the 50 randomly selected chemicals (see Table A), a list of the 100 eligible candidates (see attached Table 1), and the table of random numbers (see attached Table 2) are also available on the OEHHA Web site at the following address: /. The remaining 50 chemicals will be part of the pool from which future selections will occur. Future selections will be published in the CRNR and also on the OEHHA Web site.

OEHHA will evaluate the 50 randomly selected chemicals for consideration of carcinogenicity. Over the next several months draft priority assignments of the 50 randomly selected chemicals will be made. Consistent with the previous random selection rounds, each chemical will receive a screening toxicity evaluation based on a brief review of the available scientific literature. A draft priority ranking of "High" or "Not High" will be assigned to each of the 50 chemicals, based on the evidence of carcinogenicity. OEHHA will hold a public workshop and a 60-day public comment period to solicit oral as well as written comment on the draft priority rankings. Chemicals receiving a final priority ranking of "High" toxicity concern will be considered first by the Carcinogen Identification Committee (CIC.) To facilitate the CIC's consideration, hazard identification documents are prepared that summarize the scientific evidence on the carcinogenicity of the chemical.

OEHHA is committed to an open and public process in the implementation of Proposition 65. The posting of the results of the random selection and prioritization of chemicals for consideration by the CIC of the Science Advisory Board is part of that process.

For inquiries on Proposition 65 or for copies of Table A, Table 1 or Table 2, please call or write to:

Cynthia Oshita
Street Address: 1001 I Street
Sacramento, California 95814
Mailing Address: P.O. Box 4010
Sacramento, California 95812-4010
FAX (916) 323-8803
(916) 445-6900