September 21 and 22, 2010 Meeting of the Carcinogen Identification Committee

The California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65; Health and Safety Code Section 25249.8 et seq.).

The Carcinogen Identification Committee of OEHHA’s Science Advisory Board identifies chemicals for addition to the Proposition 65 list: The Committee serves as the “State’s qualified experts” for determining whether a chemical has been clearly shown, through scientifically valid testing according to generally accepted principles, to cause cancer.

A public meeting of this committee will be held on Tuesday and Wednesday, September 21 and 22, 2010 at the California Environmental Protection Agency Headquarters Building, Sierra Hearing Room, at 1001 I Street, Sacramento, California. Each day of the meeting will begin at 10:00 a.m. and will last until 5:00 p.m. or until all business is conducted. Committee items that are not completed on September 21 will be heard on September 22.

If you have special accommodation or language needs, please contact the Proposition 65 Office at (916) 445-6900 or sam.delson@oehha.ca.gov. TTY/TDD/Speech-to-Speech users may dial 7-1-1 for the California Relay Service.

The tentative agenda for this meeting is given below. The order of items on the agenda is provided for general reference only. The order in which items are taken up by the Committee is subject to change at the discretion of the Chair.

I. WELCOME AND OPENING REMARKS

II. CONSIDERATION OF CHEMICALS AS KNOWN TO THE STATE TO CAUSE CANCER

A. 1,3-Dichloro-2-propanol (1,3-DCP)

• Staff presentation
• Committee discussion
• Public comments
• Committee discussion and decision

B. 3-Monochloropropane-1,2-diol (3-MCPD)

• Staff presentation
• Committee discussion
• Public comments
• Committee discussion and decision

III. PRIORITIZATION OF CHEMICALS FOR CARCINOGEN IDENTIFICATION COMMITTEE REVIEW

• Staff presentation
• Committee members discuss and propose priority rankings for each of the 27 chemicals
• Committee discussion
• Public comments
• Committee discussion and recommendations

IV. UPDATE OF THE SECTION 27000 LIST OF CHEMICALS WHICH HAVE NOT BEEN ADEQUATELY TESTED AS REQUIRED

V. STAFF UPDATES

VI. SUMMARY OF COMMITTEE ACTIONS

Meeting Synopsis and Slide Presentations Carcinogen Identification Committee Meeting Held on September 21, 2010

A meeting of the Proposition 65 Carcinogen Identification Committee (CIC) was held on September 21, 2010, at the California Environmental Protection Agency Headquarters Building in Sacramento, California. The Committee considered the listing of 1,3-dichloro-2-propanol (1,3-DCP) and 3-monochloropropane-1,2-diol (3-MCPD) as known to the state cause cancer. The Committee also provided OEHHA with its advice concerning the relative priority of 27 chemicals for possible hazard identification material preparation. Following is a summary of that meeting.

SUMMARY OF THE LISTING DECISION FOR 1,3-DICHLORO-2-PROPANOL (1,3-DCP) AND 3 MONOCHLOROPROPANE-1,2-DIOL (3-MCPD)

Following a staff presentation, comments from the public and committee discussion, the CIC determined that both 1,3-DCP and 3.MCPD have been clearly shown to cause cancer; and therefore were added to the Proposition 65 chemical list effective October 8, 2010.

Follow these links to the slide presentations made at the meeting by staff of the California Environmental Protection Agency’s Office of Environmental Health Hazard Assessment (OEHHA) and members of the public:

• 1,3-Dichloro-2-propanol (1,3-DCP), David Morry, Ph.D,. OEHHA
• 3-Monochloropropane-1,2-diol (3-MCPD), Rajpal S. Tomar, Ph.D., OEHHA
• 1,3-DCP and 3-MCPD, Lois Haighton, CANTOX

SUMMARY OF CHEMICAL PRIORITIZATION DISCUSSION
The CIC recommended that 6 of the 27 chemicals referred to them for advice and consultation be placed in the ‘high’ priority group, 12 chemicals be placed in the ‘medium’ priority group, and the remaining 9 be placed in the ‘low’ priority group (see table below for specific suggestions concerning chemical priority assignments).

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