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4,4-Methylenedianiline

CAS Number

101-77-9

Synonym

Curithane; DAPM; DDM; Diaminodiphenylmethane; 4,4-diphenylmethanediamine; Epicure DDM; Methylenebis(aniline); Methylenedianiline; Tonox; MDA; 4,4'-Diaminodiphenylmethane

Occurrence/Use

Chemical intermediate in production of polyurethane foams, epoxy resins and adhesives, high-performance polymers, azo dyes, and elastomeric fibers; corrosion inhibitor, antioxidant

4,4-Methylenedianiline

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 
4.6 E-4
Inhalation Slope Factor (mg/kg-day)-1: 
1.6 E+0
Oral Slope Factor (mg/kg-day)-1: 
1.6 E+0
Comments/References: 

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Air

Chronic REL

Chronic Inhalation REL (μg/m3): 
20
Chronic Target Organs: 
Eyes, alimentary system (liver)
Human Data: 
No
Last Chronic REL Revision: 
2001
Chronic Reference Exposure Levels Comments: 

Proposition 65

Chemical Status

Cancer: 
Currently listed

Cancer

Listed as causing: 
Cancer
Date of Listing: 
01/01/1988
Basis for Listing: 
State's Qualified Experts

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
0.4 µg/day
Last NSRL/MADL Revision: 
1992

Documents, Presentations, and Publications

Cancer: