Epichlorohydrin

CAS Number

106-89-8

Synonym

DL-a-epichlorohydrin; Chloropropylene; 1-Chloro-2,3-Epoxy Propone; (Chloromethyl) Ethylene Oxide; Chloropropylene Oxide; Ech; Glycerol Epichlorohydrin; 1-Chloro-2,3-epoxypropane; gamma-Chloropropylene oxide; chloro-2,3-epoxypropane; (chloromethyl)oxirane; 2-(Chloromethyl)oxirane; chloromethyl; 3-chloro-1,2-epoxypropane; 3-chloro-1,2-propylene oxide; alpha-epichlorohydrin; 1,2-epoxy-3-chloropropane

Occurrence/Use

Production of synthetic materials, including epoxy and phenoxy resins, synthetic glycerol, and elastomers; solvent, fumigant; chemical intermediate

Epichlorohydrin

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 2.3 E-5
Inhalation Slope Factor (mg/kg-day)-1: 8.0 E-2
Oral Slope Factor (mg/kg-day)-1: 8.0 E-2
Comments/References:

OEHHA 2009. Air Toxics Hot Spots Program Technical Support Document for Cancer Potencies. Appendix B. Chemical-specific summaries of the information used to derive unit risk and cancer potency values. Updated 2011.

Air

Acute RELs

Acute REL (μg/m3): 1300
Species: Human
Acute REL Toxicologic Endpoint: Respiratory and eye irritation
Acute REL Target Organs: Respiratory system, eyes
Severity: Mild
Last Acute REL Revision: 1999
Acute Reference Exposure Levels Comments:

OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D2.

Chronic REL

Chronic Inhalation REL (μg/m3): 3
Chronic Target Organs: Respiratory system, eyes
Human Data: No
Last Chronic REL Revision: 2000
Chronic Reference Exposure Levels Comments:

OEHHA 2008. Technical Supporting Document for Noncancer RELs, Appendix D3

 

Proposition 65

Chemical Status

Cancer: Currently listed
Reproductive Toxicity : Currently listed

Cancer

Cancer - Listing Mechanism
State's Qualified Experts
Listed as causing : Listed as causing: Cancer
Date of Listing:

Reproductive Toxicity

Listed as causing: Male Reproductive Toxicity
Male Reproductive Toxicity
Date of Listing:
Basis for Listing : Authoritative Bodies-US Environmental Protection Agency

Safe Harbor Levels

No Significant Risk Level (NSRL)
9 µg/day
Cancer