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Melphalan

CAS Number

148-82-3

Synonym

Alanine nitrogen mustard; Alkeran; Alanine nitrogen mustard; CB 3025; Melfalan; Mephalan; NCI-C04853; L-PAM; Phenylalanine mustard; L-phenylalanine mustard; Phenylalanine nitrogen mustard; Sarcoclorin; L-sarcolysin; P-l-sarcolysin; Sarcolysine; L-3-(para-(bis(2-chloroethyl)amino)phenyl)alanine; 4-(bis(2-chloroethyl)amino)-l-phenylalanine; Para-di(2-chloroethyl)aminophenylalanine

Occurrence/Use

Medicine (alkylating agent- multiple myeloma, ovarian cancer)

Melphalan

Cancer Potency Information

Latest Criteria: 
Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 
3.7 E-2
Inhalation Slope Factor (mg/kg-day)-1: 
1.3 E+2
Oral Slope Factor (mg/kg-day)-1: 
1.3 E+2
Comments/References: 

Proposition 65

Chemical Status

Cancer: 
Currently listed
Reproductive Toxicity: 
Currently listed

Cancer

Listed as causing: 
Cancer
Date of Listing: 
02/27/1987
Basis for Listing: 
Labor Code

Reproductive Toxicity

Listed as causing: 
Developmental Toxicity
Developmental Toxicity
Date of Listing: 
07/01/1990
Basis for Listing: 
Formally Required

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
0.005 µg/day
Last NSRL/MADL Revision: 
1992

Documents, Presentations, and Publications

Cancer: