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n-Nitroso-n-Methylurea

CAS Number

684-93-5

Synonym

Carbamide, N-methyl-N-nitroso; Methylnitrosourea; NMU; N-methyl-n-nitrosourea; 1-methyl-1-nitrosourea; N-nitroso-n-methylcarbamide; Nitrosomethylurea; 1-nitroso-1-methylurea

Occurrence/Use

Research chemical (induces cancer). Used in clinical trials as an anti-tumor agent. Formerly used to produce diazomethane; patented for use as a polymerization agent.

n-Nitroso-n-Methylurea

Cancer Potency Information

Inhalation Unit Risk (μg/cubic meter)-1: 
3.4 E-2
Inhalation Slope Factor (mg/kg-day)-1: 
1.2 E+2
Oral Slope Factor (mg/kg-day)-1: 
1.2 E+2
Comments/References: 

This value was used as the basis of the No Significant Risk Level that was adopted in Title 22 California Code of Regulations, Section 12705, Subsection (b) for the purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65).

Proposition 65

Chemical Status

Cancer: 
Currently listed

Cancer

Listed for: 
Cancer
Date of Listing: 
10/01/1987
Basis for Listing: 
State's Qualified Experts

Safe Harbor Levels

Cancer
No Significant Risk Level (NSRL): 
0.006 µg/day