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December 4, 2002 Meeting of the Science Advisory Board's Developmental and Reproductive Toxicant (DART) Identification Committee

OEHHA has prepared the draft hazard identification document for sodium saccharin and announces the availability of the draft document entitled: "Evidence on the Carcinogenicity of Sodium Saccharin."

OEHHA has prepared the draft hazard identification documents for diuron and bromacil lithium salt and announces the availability of the draft documents entitled: "Evidence on the Developmental and Reproductive Toxicity of Diuron," and "Evidence on the Developmental and Reproductive Toxicity of Bromacil Lithium Salt."

OEHHA has prepared the draft hazard identification document for phenelzine and its acid salts and announces the availability of the draft document entitled: "Evidence on the Carcinogenicity of phenelzine and its acid salts."

OEHHA has provided a number of comments and concerns on the risk characterization methodology and conclusions of the TAC documents for Chlorpyrifos. These comments and our recommendations, as well as suggested clarifications, additions and corrections, are contained in this report.OEHHA has also submitted findings on the active ingredient Chlorpyrifos for your review. These findings were prepared in response to the TAC documents prepared by the Department of Pesticide Regulation (DPR).

Amendment to Section 12705. Specific Regulatory Levels Posing No Significant Risk: benzofuran, N-carboxymethyl-N-nitrosourea, p-chloro-o-toluidine hydrochloride, 3,3'-dimethoxybenzidine; 3,3'-dimethoxybenzidine dihydrochloride, 3,3'-dimethylbenzidine, 3,3'-dimethylbenzidine dihydrochloride, isobutyl nitrite, 2-methylaziridine (propyleneimine), nalidixic acid, phenyl glycidyl ether, o-phenylenediamine, o-phenylenediamine dihydrochloride, tetranitromethane, and 2,6-xylidine and Amendment to Section 12805. Specific Regulatory Levels: Reproductive Toxicants: linuron

Notice of Amendments to Text of Regulations Title 22, California Code of Regulations, Sections 12601 and 12201.

OEHHA has provided a number of comments on the risk characterization methodology and conclusions on the draft RCD for Methyl Bromide (Aggregate). These comments and our recommendations, as well as suggested clarifications, additions and corrections, are contained in the attachment.

Notice of Modifications to Text of Regulations Title 22, California Code of Regulations Sections 12705 and 12805

The Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 65) requires the Governor to publish, and update at least annually, a list of chemicals known to the State to cause cancer or reproductive toxicity. The Office of Environmental Health Hazard Assessment (OEHHA) is the lead agency for the implementation of Proposition 65.