Domoic Acid Workshop

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Evaluating the State of the Science

and Implications for Human Toxicity

Register for free here. Space is limited, so register early.

Directions and parking information are available at the UC Davis website

 

AGENDA

 

9:00 – 9:20      Opening Remarks: Workshop Goal and Purpose

Office of Environmental Health Hazard Assessment (OEHHA) and UC Davis

9:20 – 9:40      Prince Edward Island: 1987 Domoic Acid Event

Andrew Tasker, University of Prince Edward Island

SESSION I  Moderator: Susan Klasing, OEHHA

9:40 – 10:10    What Marine Mammals Tell Us about Potential Human Toxicity Endpoints

Frances Gulland, Marine Mammal Center (Sausalito)

10:10 – 10:25  BREAK

10:25 – 10:55  Chronic, Low-level Domoic Acid Exposure in Humans: the CoASTAL Cohort

Lynn Grattan, University of Maryland

10:55 – 11:25  Disposition, Pharmacokinetics and Understanding the Human Dose

John Ramsdell, National Oceanic and Atmospheric Administration

11:25 – 12:00  Discussion Panel

Irva Hertz-Picciotto, UC Davis (Facilitator); Elaine Faustman, University of Washington (UW); Melissa Miller, CA Department of Fish and Wildlife; Session I speakers; Audience Q&A

12:00 – 1:00    LUNCH

SESSION II Moderator: Shannon Murphy, OEHHA

1:00 – 1:30      Domoic Acid Experiments in Mice: Exposure, Pharmacokinetics, Pathways of Interest, and Endpoints  

Elaine Faustman, University of Washington

1:30 – 2:00      Domoic Acid Experiments in Rats: Exposure, Neurodevelopmental Toxicity, and Behavioral Teratology

Tracy Doucette, University of Prince Edward Island

2:00 – 2:30      Domoic Acid Experiments in Mice and Endpoints Relevant to Autism Spectrum Disorders

Garet Lahvis, Oregon Health Sciences University

2:30 – 3:05      Discussion Panel

Pam Lein, UC Davis (Facilitator); Isaac Pessah, UC Davis; John Ramsdell, NOAA; Session II speakers; Audience Q&A

3:05 – 3:20      BREAK

SESSION III Moderator: Gina Solomon, California Environmental Protection Agency

3:20 – 3:45      Putting it all Together: Models, Endpoints and Dose-Response

Andrew Tasker, University of Prince Edward Island

3:45 – 4:45      Discussion Panel: What do the Data and Models Tell Us about Human Toxicity?

Irva Hertz-Picciotto, UC Davis (Facilitator); Elaine Faustman, UW; Gina Solomon, CalEPA; Andrew Tasker, UPEI; Audience Q&A

4:45 – 5:00      Closing Remarks

Lauren Zeise, OEHHA

 

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