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Methylene Diphenyl Diisocyanate (MDI)

CAS Number

101-68-8

Synonym

p,p'-Diphenylmethane diisocyanate; p,p'-Methylenebis[phenyl isocyanate]; Bis(p-isocyanatophenyl)methane; Diphenylmethane diisocyanate; Diphenylmethane p,p'-diisocyanate; Methylenebis[p-phenyl isocyanate]; 4,41-MDI; MDI; Monomeric MDI; NCI-C50668

Occurrence/Use

Manufacture of lacquer coatings, polyurethane resins, and spandex fibers

Methylene Diphenyl Diisocyanate

Cancer Potency Information

Latest Criteria: 
Chronic Reference Exposure Levels

Air

Acute RELs

Acute REL (μg/m3): 
12
Species: 
Rat
Acute REL Target Organs: 
Respiratory system
Last Acute REL Revision: 
03/30/2016
Acute Reference Exposure Levels Comments: 

8-Hour RELs

8-Hour Inhalation REL (μg/m3): 
0.16
Last 8-Hour REL Revision: 
03/30/2016
8-Hour Reference Exposure Levels Comments: 

Chronic REL

Chronic Inhalation REL (μg/m3): 
0.08
Chronic Target Organs: 
Respiratory system
Human Data: 
no
Last Chronic REL Revision: 
03/30/2016
Chronic Reference Exposure Levels Comments: