Diethylstilbestrol

CAS Number

56-53-1

Synonym

Antigestil; Bufon; Comestrol; DEB; DES; Distilbene; Estrobene; Fonatol; Grafestrol; Iscovesco; Microest; Milestrol; Oestrogenine; Oestromenin; Palestrol; Serral; Sibol; Stilbetin; Stilboefral; Stilboestrol; Stilkap; Synestrin; Synthoestrin; Trans-diethylstilbesterol

Occurrence/Use

Veterinary medicine (canine incontinence). Formerly used in medicine to prevent spontaneous abortion, treat prostate cancer and breast cancer; marketing in US ended in 1997. Formerly used as growth hormone in beef and poultry industries (phased out in late 1970s).

Diethylstilbestrol

Cancer Potency Information

Latest Criteria: Proposition 65 NSRLs/MADLs
Inhalation Unit Risk (μg/cubic meter)-1: 1.0 E-1
Inhalation Slope Factor (mg/kg-day)-1: 3.5 E+2
Oral Slope Factor (mg/kg-day)-1: 3.5 E+2
Comments/References:

OEHHA 1992. Expedited Cancer Potency Values and Proposed Regulatory Levels for Certain Proposition 65 Carcinogens.

Proposition 65

Chemical Status

Cancer: Currently listed
Reproductive Toxicity : Currently listed

Cancer

Cancer - Listing Mechanism
Labor Code
Listed as causing : Listed as causing: Cancer
Date of Listing:

Reproductive Toxicity

Listed as causing: Developmental Toxicity
Developmental Toxicity
Date of Listing:
Basis for Listing : Formally Required

Safe Harbor Levels

No Significant Risk Level (NSRL)
0.002 µg/day
Cancer
Last NSRL/MADL Revision: 1992

Documents, Presentations, and Publications

Cancer:

Public notices related to this chemical