Draft Report: Child-Specific Reference Dose (chRD) for School Site Risk Assessment: Paraquat

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The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is making available for review and comment the Draft Report, “Development of Health Criteria for School Site Risk Assessment Pursuant to Health and Safety Code (HSC) Section 901(g): Proposed Child-Specific Reference Dose (chRD) for Paraquat.” 

HSC §901(g) requires the Office of Environmental Health Hazard Assessment (OEHHA), in consultation with the appropriate entities within the California Environmental Protection Agency, to identify those chemical contaminants commonly found at school sites and determined by OEHHA to be of greatest concern based on child-specific physiological sensitivities.  HSC 901(g) also requires OEHHA to annually evaluate and publish, as appropriate, numerical health guidance values (HGVs) or chRDs for those chemical contaminants.

The draft chRD for paraquat being considered at this time is 7 x 10‑5 mg/kg-day.  In developing the chRD, OEHHA selected two young animal studies and two adult animal studies.  Collectively these studies paint a cohesive picture that paraquat is a neurotoxicant and impacts brain functions.  The chRD is based on the lowest observed adverse effect level (LOAEL) of 0.07 mg/kg-day from one of the studies.

This public review and comment period follows the requirements set forth in Health and Safety Code Section 57003 for receiving public input. 

  • A public workshop will be held from 10:00 AM to 12:00 PM on January 13, 2010, in the Conference Room 230 on the second floor of the Joe Serna (Cal/EPA headquarters) Building, 1001 I Street, Sacramento.  Oral and written comments received at the workshop and during the comment period will be considered during the revision of the draft document.  Because there will be no official transcript of the meeting, we recommend that oral comments also be submitted in writing.
  • The Office of Environmental Health Hazard Assessment (OEHHA) received a request to extend the comment period.  On January 1, 2010, after careful consideration for providing adequate time for the review and comment and to finalize the document in a timely fashion, OEHHA decided to extend the end of the comment period from the original ending date of January 22, 2010. 
  • OEHHA requests that written comments on this draft report be submitted by 5:00 PM, February 22, 2010.  The draft report can be downloaded below. Comments can be submitted using the address, fax number, or email address below. 

If you would like to receive further information on this announcement or have questions, please contact Carmen Milanes by email at carmen.milanes@oehha.ca.gov, by phone at (916) 323-4153, or at the address below.

Carmen Milanes
Office of Environmental Health Hazard Assessment
P.O. Box 4010, MS-12B
1001 I Street
Sacramento, California 95812-4010
FAX: (916) 322-9705