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Child- Specific Reference Dose - Notice of a Public Comment Period and Public Workshop on the Child-Specific Reference Dose (chRD) for Paraquat for use in Assessing Health Risks at Existing and Proposed School Sites
Follow this link to download the Draft Report: Development of Health Criteria for School Site Risk Assessment Pursuant to Health and Safety Code (HSC) Section 901(g): PROPOSED CHILD-SPECIFIC REFERENCE DOSE (chRD) FOR PARAQUAT.
The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency is making available for review and comment the Draft Report, “Development of Health Criteria for School Site Risk Assessment Pursuant to Health and Safety Code (HSC) Section 901(g): PROPOSED CHILD-SPECIFIC REFERENCE DOSE (chRD) FOR PARAQUAT.”
HSC §901(g) requires the Office of Environmental Health Hazard Assessment (OEHHA), in consultation with the appropriate entities within the California Environmental Protection Agency, to identify those chemical contaminants commonly found at school sites and determined by OEHHA to be of greatest concern based on child-specific physiological sensitivities. HSC 901(g) also requires OEHHA to annually evaluate and publish, as appropriate, numerical health guidance values (HGVs) or chRDs for those chemical contaminants.
The draft chRD for paraquat being considered at this time is 7 x 10‑5 mg/kg-day. In developing the chRD, OEHHA selected two young animal studies and two adult animal studies. Collectively these studies paint a cohesive picture that paraquat is a neurotoxicant and impacts brain functions. The chRD is based on the lowest observed adverse effect level (LOAEL) of 0.07 mg/kg-day from one of the studies.
This public review and comment period follows the requirements set forth in Health and Safety Code Section 57003 for receiving public input. A public workshop will also be held from 10:00 AM to 12:00 PM on January 13, 2010, in the Conference Room 230 on the second floor of the Joe Serna (Cal/EPA headquarters) Building, 1001 I Street, Sacramento. Oral and written comments received at the workshop and during the comment period will be considered during the revision of the draft document. Because there will be no official transcript of the meeting, we recommend that oral comments also be submitted in writing.
The draft report can be downloaded from the OEHHA website at www.oehha.ca.gov. OEHHA requests that written comments on this draft report be submitted by 5:00 PM, January 22, 2010. Comments can be submitted using the address, fax number, or email address below. If you would like to receive further information on this announcement or have questions, please contact our office at (916) 324-2829 or the address below.
Mr. Leon Surgeon
Integrated Risk Assessment Branch
Office of Environmental Health Hazard Assessment
P.O. Box 4010
1001 I Street, MS-12B
Sacramento, California 95812-4010
FAX: (916) 322-9705