Chemicals Listed Effective May 3, 2011 As Known To The State Of California To Cause Cancer: androstenedione, dibromoacetonitrile, hexachlorobutadiene, and malonaldehyde, sodium salt

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The Office of Environmental Health Hazard Assessment (OEHHA) within the California Environmental Protection Agency is adding four chemicals -- androstenedione (CAS No. 63-05-8), dibromoacetonitrile (CAS No. 3252-43-5), hexachlorobutadiene (CAS No. 87-68-3), and malonaldehyde, sodium salt (CAS No. 24382-04-5) -- to the list of chemicals known to the state to cause cancer for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 651).  The listing of the four chemicals is effective May 3, 2011. 

The listings of androstenedione, dibromoacetonitrile, and malonaldehyde, sodium salt are based on formal identifications by an authoritative body2, the National Toxicology Program (NTP), that the chemicals cause cancer.  The listing of hexachlorobutadiene is based on a formal identification by an authoritative body2, the U.S. Environmental Protection Agency (U.S. EPA), that the chemical causes cancer.  The criteria used by OEHHA for the listing of chemicals under the “authoritative bodies” mechanism can be found in Title 27, Cal. Code of Regs., section 25306. 

The documentation supporting OEHHA’s determination that the criteria for administrative listing have been satisfied for these chemicals is included in the Notice of Intent to List:  Androstenedione, Dibromoacetonitrile, Hexachlorobutadiene, and Malonaldehyde, sodium salt, published in the March 4, 2011 issue of the California Regulatory Notice Register (Register 2011, No. 9‑Z). 

A complete, updated Proposition 65 list is published elsewhere in this issue of the California Regulatory Notice Register and is available on the OEHHA website at http://www.oehha.ca.gov.

Chemical

CAS No.

Toxicological Endpoint

Listing Mechanism3

Androstenedione

63-05-8

cancer

AB (NTP)

Dibromoacetonitrile

3252-43-5

cancer

AB (NTP)

Hexachlorobutadiene

87-68-3

cancer

AB (U.S. EPA)

Malonaldehyde, sodium salt

24382-04-5

cancer

AB (NTP)

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Footnotes and References

1Health and Safety Code, section 25249.5 et seq.

2See Health and Safety Code, section 25249.8(b) and Title 27, Cal. Code of Regs., section 25306.

3Listing mechanism:  AB – “authoritative bodies” mechanism (Title 27, Cal. Code of Regs. section 25306).