Bisphenol-A Listed as Known to the State of California to Cause Reproductive Toxicity

Effective May 11, 2015, the Office of Environmental Health Hazard Assessment (OEHHA) is adding bisphenol A (BPA) (CAS No. 80-05-7) to the list of chemicals known to the state to cause reproductive toxicity for purposes of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition 651).

BPA was considered by the Developmental and Reproductive Toxicant Identification Committee (DARTIC) in its official capacity as the “state’s qualified experts” (SQE) at a public meeting held on May 7, 2015. The DARTIC determined that BPA was clearly shown through scientifically valid testing according to generally accepted principles to cause reproductive toxicity, based on the female reproductive endpoint.2 Regulations for listing of chemicals by the DARTIC are set out in Title 27, California Code of Regulations, section 25305(b)(1).

A complete, updated chemical list is available at and will be published in the May 22, 2015 issue of the California Regulatory Notice Register.

In summary, the chemical in the table below is listed under Proposition 65 as known to the State to cause reproductive toxicity (female reproductive toxicity) effective May 11, 2015.



Toxicological Endpoints

Listing Mechanism*

Bisphenol A (BPA)


Female reproductive toxicity


Footnotes and References

* SQE – “state’s qualified experts” mechanism (Health and Safety Code section 25249.8(b) and Title 27, Cal. Code of Regs., section 25305(b)(1)).

1Health and Safety Code section 25249.5 et seq.

2Health and Safety Code section 25249.8(b)