The California Environmental Protection Agencys Office of
Environmental Health Hazard Assessment (OEHHA) is the lead agency
for the implementation of the Safe Drinking Water and Toxic
Enforcement Act of 1986 (Proposition 65; Health and Safety Code
25249.5 et seq.).
The Carcinogen Identification Committee of OEHHAs Science
Advisory Board provides advice on the list of chemicals known to
the State to cause cancer which by the Proposition 65 mandate must
be updated annually. The Committee serves as the States qualified
experts for rendering an opinion as to whether a chemical has been
clearly shown, through scientifically valid testing according to
generally accepted principles, to cause cancer.
OEHHA has developed a procedure for prioritizing candidate chemicals
for consideration under Proposition 65 by the States qualified
experts, described in, "Procedure for Prioritizing Candidate
Chemicals for Consideration Under Proposition 65 by the States
Qualified Experts," May 1997, and available on the Internet
On October 3, 1997, OEHHA released for public comment draft priority
assignments and draft data summaries for 28 chemicals with respect
to their potential to cause cancer. OEHHA announced the final priority
assignments for these chemicals in a separate notice published elsewhere
in this issue of the California Regulatory Notice Register.
In accordance with OEHHAs prioritization procedure, all chemicals
with final priority assignments of high carcinogenicity
concern are placed on the final Candidate List (Table 1). Chemicals
are then selected from the Candidate List for the development of
draft cancer hazard identification documents and subsequent consideration
for listing by the Carcinogen Identification Committee of OEHHAs
Science Advisory Board. Consistent with OEHHAs current (May
1997) prioritization procedure, chemicals with the highest level
of exposure concern will be selected first from the Candidate List.
TABLE 1. Final Candidate List as of June 12, 1998
Level Of Exposure Concern
CASRN = Chemical Abstracts Service Registration Number
n.i.c.= No Identified Concern
At this time, OEHHA requests information relevant to the assessment
of the evidence of carcinogenicity on the following chemicals:
p-chloronitrobenzene [CAS No. 100-00-5]
estragole [CAS No. 140-67-0]
trichloroacetic acid [CAS No. 76-03-9]
bis(2-chloro-1-methylethyl)ether [CAS No. 108-60-1]
2-aminofluorene [CAS No. 153-78-6]
4-amino-2-nitrophenol [CAS No. 119-34-6]
Interested parties or members of the public wishing to provide
information relevant to the assessment of these chemicals should
forward such information to the address given below. The publication
of this notice marks the start of a 60-day data call-in period.
This period ends on August 11, 1998. The information received during
this data call-in period will be reviewed and considered by OEHHA
as it develops the draft cancer hazard identification documents
on these compounds.
OEHHA welcomes public participation and public input as part of
these scientific assessments. If there is sufficient public interest
in a specific candidate chemical, a workshop or other public forum
will be held to encourage scientific dialogue prior to completion
of the draft hazard identification document.
Notification of the availability of the hazard identification documents
and of the time, date, location, and agenda of any workshops and
of the next meeting of the Carcinogen Identification Committee will
be provided in subsequent notices published in the California
Regulatory Notice Register and posted on OEHHAa Internet.
It is anticipated that the draft hazard identification documents
will be made available for a 60-day comment period prior to the
committee meetings at which these chemicals will be considered.
Relevant information on these chemicals should be sent in triplicate
by mail or fax to:
Office of Environmental Health Hazard Assessment
Post Office Box 4010
Sacramento, CA 95812-4010
Fax (916) 327-1097
Telephone (916) 445-6900
Relevant information may also be delivered in person or by courier
to the above address.
In order to be considered, the relevant information must be
received at OEHHA by 5:00 PM on August 11, 1998.
For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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