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California Environmental Protection Agency’s Office of Environmental
Health Hazard Assessment (OEHHA) is the lead agency for the implementation
of the Safe Drinking Water and Toxic Enforcement Act of 1986 (Proposition
65). The Developmental and Reproductive Toxicant (DART) Identification
OEHHA’s Science Advisory Board advises and assists OEHHA in compiling
the list of chemicals known to the State to cause reproductive toxicity,
which is mandated by Health and Safety Code Section 25249.8. The
Committee serves as the State’s qualified experts for rendering
an opinion whether a chemical has been clearly shown through scientifically
valid testing according to generally accepted principles to cause
July 16, 1999, OEHHA published a public notice in the California
Regulatory Notice Register
(CRNR) (Register 99, No. 29-Z) requesting information relevant
to the assessment of the reproductive and developmental toxicity
of: 2,4-D 2-ethylhexyl ester, 2,4-D 2-ethyl-4-methylpentyl
ester, fenbutatin oxide, propachlor, quizalofop-ethyl, sodium nitrite,
and triphenyltin hydroxide. In accordance with OEHHA’s process for
preparing information on candidate chemicals for review by the State’s
qualified experts, OEHHA reviews the available literature and data
on the candidate chemicals, including that information submitted
by interested parties and develops a hazard identification document
for each chemical based on the evidence of reproductive toxicity
for the chemical.
public notice published in the CRNR on July 16, 1999 stated that
2,4-D 2-ethylhexyl ester and 2,4-D 2-ethyl-4-methylpentyl
ester are individual isooctyl esters of 2,4-D, and that 2,4-D isooctyl
ester has been noticed as being under consideration for administrative
listing under Proposition 65 (CRNR,
August 22, 1997, Register 97, No. 34-Z). If 2,4-D isooctyl ester
is listed under Proposition 65 as causing reproductive toxicity,
2,4-D 2-ethylhexyl ester and 2,4-D 2-ethyl-4-methyl-pentyl
ester may or may not be considered by the DART Identification Committee.
Although preparation of hazard identification documents for these
two chemicals will not begin until this is resolved, a request for
information was made in the event documents are prepared. If hazard
identification documents are prepared for 2,4-D 2-ethylhexyl ester
and 2,4-D 2-ethyl-4-methylpentyl ester, a second data call-in period
will be announced so that the most recent relevant information may
of the hazard identification document for propachlor is pending
receipt of studies provided to the U.S. Environmental Protection
Agency in support of propachlor’s federal pesticide registration.
Because of the probable delay in preparation of the hazard identification
document on propachlor, a second data call-in period will be announced
when preparation of the document is initiated.
of the hazard identification documents for fenbutatin oxide
and quizalofop-ethyl is underway. OEHHA anticipates completion
and public release for comment of the hazard identification documents
for these two chemicals in the Fall of 1999 so that the two candidate
chemicals may be brought before the DART Identification Committee
for consideration for listing at its meeting on December 13, 1999.
The time and location of the meeting have not yet been determined,
but will be provided in a future public notice.
the initial stages of preparing hazard identification documents
for sodium nitrite and triphenyltin hydroxide, OEHHA
staff determined that additional time is needed to fully review
and consider the complex issues regarding these two chemicals. In
addition, OEHHA received requests to extend the request for information
period for sodium nitrite. Since we anticipate that both chemicals
will be brought before the DART Identification Committee for consideration
at a meeting in early 2000, instead of December 13, 1999, OEHHA
is extending the request for information period for sodium nitrite
and triphenyltin hydroxide to September 15, 1999.
of the availability of the individual draft hazard identification
documents and of the time, date, location, and agenda of the meetings
of the DART Identification Committee where the chemicals will be
considered will be provided in future notices published in the California
Regulatory Notice Register and posted on OEHHA’s Home Page at
www.oehha.ca.gov. The draft hazard identification documents will
be made available for public comment prior to the committee meeting
at which the chemical is considered.
information on sodium nitrite and/or triphenyltin hydroxide should
be sent in triplicate by mail or fax to:
Office of Environmental Health Hazard Assessment
1001 I Street,
Sacramento, CA 95814
our mailing address:
Post Office Box 4010
Sacramento, CA 95812-4010.
information may also be delivered in person or by courier to the
above address. In order to be considered, the relevant information
must be postmarked (if sent by mail) or received at OEHHA (if hand-delivered
or sent by fax) by 5:00 p.m. on Wednesday, September 15, 1999.
a copy of the CRNR notice as a PDF file.
You will need the free program Adobe Acrobat Reader to view or
print PDF files
For questions regarding Proposition 65, please contact the Cynthia
Oshita in the Proposition 65 Implementation Program
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